Interstate 80 runs through the middle of Pennsylvania and is one of the state's main east-west highways, along with the Pennsylvania Turnpike to the south. It directly serves DuBois, Clearfield, Bloomsburg, and the Pocono Mountain cities of Tannersville and Stroudsburg, and connects with State College via Interstate 99, Williamsport via U.S. Route 220 and Interstate 180, and Wilkes-Barre/Scranton by way of interstates 81 and 380. In all, I-80 spends 311 miles in Pennsylvania, between the Ohio state line and the Delaware Water Gap bridge into New Jersey.