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Interstate 80 east - Ohio line to Brookville

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Eastbound Interstate 80 enters Pennsylvania from Ohio in West Middlesex Township, Mercer County. (4-10-2026)

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A Pennsylvania welcome center sits half a mile away. (4-10-2026)

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Much of I-80 in Pennsylvania is designated the Z.H. Confair Memorial Highway as well as the Keystone Shortway. (4-10-2026)

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The welcome center sits just ahead on the right. (4-10-2026)

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At right, an AM radio frequency is displayed for drivers to tune into for travel information. (4-10-2026)

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The highway goes on to cross Pennsylvania Route 718 (Sieg Hill Road). (4-10-2026)

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2 miles away, exit 4 intersects the northern end of Interstate 376 and Pennsylvania Route 760 (leading to Pennsylvania Route 18), serving the cities of New Castle, Sharon and Hermitage. (4-10-2026)

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Prior to exit 4, I-80 crosses the Shenango River. (4-10-2026)

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Exit 4 is designated the Gordon Ward Interchange. (4-10-2026)

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Exit 4A to I-376 east (formerly PA 60 east) is ahead to the right. (4-10-2026)

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Exit 4B comes soon afterward. To the left, there is a sign billing I-376 as the Beaver Valley Expressway. (4-10-2026)

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I-376/PA 760 cross I-80 along this pair of overpasses. (4-10-2026)

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The exit 4B gore sign, which looked different at the time of these photos due to construction along the corridor. (4-10-2026)

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The cities of Mercer and Clarion are a respective 12 and 58 miles away from here. (4-10-2026)

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I-80 goes on through fairly open land with a scattering of trees. (4-10-2026)

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Soon, the Interstate passes under Bethel-New Wilmington Road (SR 3011). (4-10-2026)

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The highway then makes its way downhill as it curves to the left. (4-10-2026)

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For a brief period, the median widens, then narrows again. (4-10-2026)

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The highway now enters a fog area. (4-10-2026)

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A series of winding curves is approaching. (4-10-2026)

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The recommended speed along these curves is 60 MPH. (4-10-2026)

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The highway next passes under Orchard Road (SR 3013). (4-10-2026)

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Soon, it eases downhill and curves to the left. (4-10-2026)

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Signs prior to the Stonepile Road overpass warn of fallen rocks. (4-10-2026)

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In 2 miles, I-80 intersects U.S. Route 19 toward Mercer at exit 15. (4-10-2026)

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A sharp curve to the left sits up ahead. (4-10-2026)

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Exit 15 can be used to reach the Thiel and Westminster Colleges. (4-10-2026)

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The curve is just after Pennsylvania Route 158's (Mercer New Wilmington Road) crossing of the Interstate. (4-10-2026)

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Exit 15 is ahead on the right. US 19 serves as the local route paralleling I-79 a few miles east. (4-10-2026)

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The exit 15 gore sign. (4-10-2026)

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I-80 reassurance follows exit 15. (4-10-2026)

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The highway goes on to a bridge over Nesh Annock Creek. (4-10-2026)

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The cities of Clarion and DuBois are a respective 47 and 83 miles from here. (4-10-2026)

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The VMS at right displays travel times to nearby interchanges. (4-10-2026)

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Exit 19, intersecting Interstate 79 with control cities of Pittsburgh and Erie, is 2 miles away. (4-10-2026)

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I-80's eastbound control city is now Clarion. (4-10-2026)

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Pennsylvania Route 58 (Mercer Grove City Road) crosses I-80 just prior to I-79. (4-10-2026)

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The exit 19A gore sign. Access to downtown Pittsburgh from southbound I-79 several miles to the south is by way of its child, Interstate 279. (4-10-2026)

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Exit 19B to I-79 north and its northern terminus in Erie is on the other side of I-79's overpasses over I-80. (4-10-2026)

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I-80 passes under Hartwick Road just past exit 19. (4-10-2026)

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Clarion and DuBois are now 43 and 79 miles away. (4-10-2026)

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At mile marker 21, I-80 enters Pine Township and crosses Clintonville Road and Springfield Church Road. (4-10-2026)

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In 2 miles, I-80 meets Pennsylvania Route 173 toward Grove City and Sandy Lake at exit 24. (4-10-2026)

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Exit 24 is ahead on the right. (4-10-2026)

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I-80 crosses PA 173 here. (4-10-2026)

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There is I-80 reassurance after exit 24. (4-10-2026)

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The Interstate goes on to cross Centertown Road. (4-10-2026)

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In 2 miles, at exit 29, I-80 meets Pennsylvania Route 8, which leads to the Franklin-Oil City area of Venango County as well as to Barkeyville. (4-10-2026)

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After the Interstate enters Venango County, gas options at exit 29 are displayed to the right. (4-10-2026)

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Meanwhile, a rest area is 1½ miles away. (4-10-2026)

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This sign points the way to exit 29, which is straight ahead as I-80 curves left. (4-10-2026)

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Exit 29 is accompanied by overhead signage closer to the beginning of the exit. (4-10-2026)

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At the PA 8 (Pittsburgh Road) overpass, the rest area is ¾ mile away. (4-10-2026)

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I-80 reassurance follows exit 29. (4-10-2026)

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The rest area entrance is on the right. (4-10-2026)

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Clarion and DuBois are now 32 and 68 miles away. (4-10-2026)

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Between exits, I-80 passes under Pennsylvania Route 208 (Clintonville Road). (4-10-2026)

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Exit 35, intersecting Pennsylvania Route 308 toward Clintonville, is a mile away. (4-10-2026)

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I-80 enters Clintonville borough before the exit. (4-10-2026)

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Before the exit, Porter Road crosses I-80 at an uphill angle. (4-10-2026)

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Exit 35 is ahead on the right. (4-10-2026)

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I-80 curves, then passes under PA 308. (4-10-2026)

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Leaving Clintonville, I-80 goes downhill toward an open field and a crossing of Coal Valley Road. (4-10-2026)

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The highway soon enters Scrubgrass Township. (4-10-2026)

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Rockdale Road (SR 3007) is the next overpass, crossing at the same angle as Porter Road. (4-10-2026)

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In 2 miles, at exit 42, I-80 intersects Pennsylvania Route 38, whose control city is Emlenton. (4-10-2026)

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In the meantime, the Interstate passes under Stone Church Road (SR 3009). (4-10-2026)

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Gas options at exit 42 are displayed to the right. (4-10-2026)

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This sign points the way to exit 42. (4-10-2026)

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I-80 crosses PA 38 right at mile marker 42. (4-10-2026)

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Afterward, I-80 briefly enters Butler County and Allegheny Township. (4-10-2026)

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An I-80 reassurance shield then appears. (4-10-2026)

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2 miles away, exit 45 intersects Pennsylvania Route 478, toward Emlenton and St. Petersburg. (4-10-2026)

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A wide curve to the left lies ahead. (4-10-2026)

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At the curve, I-80's median becomes a concrete barrier. (4-10-2026)

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At mile 44.4, I-80 begins crossing the famed Allegheny River, which takes it into Clarion County. (4-10-2026)

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After the bridge over the Allegheny, I-80 enters what PennDOT designates the Pennsylvania Wilds. (4-10-2026)

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Exit 45 can be used to reach the borough of Foxburg beside the Allegheny. (4-10-2026)

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Exit 45 is straight ahead on the right. (4-10-2026)

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The Interstate then crosses PA 478. (4-10-2026)

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After briefly re-entering Venango County, I-80 re-enters Clarion County and enters Richland Township. (4-10-2026)

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Clarion and DuBois lie a respective 16 and 51 miles away. (4-10-2026)

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At mile 47.6, I-80 passes under Master Road (SR 3020). (4-10-2026)

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The highway soon crosses Pennsylvania Route 338. (4-10-2026)

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After two bends to the left, I-80 and PA 338 cross paths again, this time with the former passing under the latter. (4-10-2026)

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Exit 53, two miles from this green sign, leads to PA 338 by way of Canoe Ripple Road, and to the borough of Knox. (4-10-2026)

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Blank blue service signs sit beside the highway prior to exit 53. (4-10-2026)

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I-80 goes over Beaver Creek and then crosses PA 338 a third time as it approaches exit 53. (4-10-2026)

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Exit 53 sits ahead on the right. (4-10-2026)

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The exit 53 gore sign. (4-10-2026)

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After exit 53, I-80 curves widely to the left once again. (4-10-2026)

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A weigh station for large trucks sits a mile away. (4-10-2026)

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The Interstate now makes its way over Tippecanoe Road, which runs through a deep valley. (4-10-2026)

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The weigh station is on the right. (4-10-2026)

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Beyond the weigh station, Huckleberry Ridge (SR 2007) crosses the Interstate. (4-10-2026)

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Afterward, an AM radio frequency for drivers to tune to for travel alerts is posted. (4-10-2026)

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Exit 60, intersecting northbound Pennsylvania Route 66 toward Shippenville, is 2 miles away. (4-10-2026)

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Before the exit, I-80 crosses Deer Creek. (4-10-2026)

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Then, it passes under East End Road (SR 4001). (4-10-2026)

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Exit 60 can be taken to Cook Forest State Park and the Allegheny National Forest. (4-10-2026)

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Exit 60 is ahead on the right. PA 66 begins a concurrency with I-80 at this interchange. (4-10-2026)

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The eastbound offramp to northbound PA 66 is a cloverleaf that loops around and back over I-80. (4-10-2026)

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Exit 62 up ahead can be used to reach the Clarion University and business district. (4-10-2026)

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I-80 and PA 66 reassurance shields then sit side by side. (4-10-2026)

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Exit 62, intersecting Pennsylvania Route 68 toward Clarion, is a mile away, and leads to the Clarion barrack of the Pennsylvania State Police. Meanwhile, I-80 begins crossing the Clarion River just ahead. (4-10-2026)

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At the end of the bridge, lodging options at exit 62 are posted to the right. (4-10-2026)

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Exit 62 is straight ahead on the right. (4-10-2026)

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The exit 62 gore sign. (4-10-2026)

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The PA 68 overpass over I-80. (4-10-2026)

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In 1¾ miles, PA 66 splits off at exit 64, bearing control cities of Clarion and New Bethlehem. (4-10-2026)

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The Interstate curves wide left before the exit. (4-10-2026)

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Exit 64 is ahead on the right. (4-10-2026)

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The exit 64 gore sign. (4-10-2026)

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With I-80 back on its own, Brookville and DuBois are a respective 13 and 33 miles away. (4-10-2026)

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The Interstate proceeds to curve wide right as its median widens and becomes tree-filled. (4-10-2026)

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A bridge over Waterson Road follows. (4-10-2026)

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Exit 70, intersecting U.S. Route 322 toward Strattanville, is 1¾ miles from the sign at right. (4-10-2026)

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I-80 enters Limestone Township and then Clarion Township prior to exit 70. (4-10-2026)

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Some of the services available at exit 70 are posted to the right. (4-10-2026)

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Exit 70 is ahead on the right. I-80 will spend about the next 50 miles running close to US 322. (4-10-2026)

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The exit 70 gore sign. (4-10-2026)

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The eastbound lanes then receive a cloverleaf onramp from US 322. (4-10-2026)

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An I-80 reassurance shield follows. (4-10-2026)

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Exit 73 intersects Pennsylvania Route 949 toward Corsica in 2 miles. (4-10-2026)

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The highway's median momentarily fills with trees before the exit. (4-10-2026)

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The sign on the right points the way to exit 73. (4-10-2026)

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The exit 73 gore sign. (4-10-2026)

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PA 949 makes its way over I-80 here. (4-10-2026)

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Past exit 73, the cities of Brookville and DuBois are 5 and 25 miles away. (4-10-2026)

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Having entered Jefferson County, I-80 glides downhill and curves gradually to the right. (4-10-2026)

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After straightening out, the highway climbs back uphill. (4-10-2026)

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The Interstate soon comes upon the Roseville Sigel Road (SR 4001) overpass. (4-10-2026)

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Exit 78, intersecting Pennsylvania Route 36 and a southbound truck route for Pennsylvania Route 28, is 2 miles away, It bears control cities of Sigel and Brookville. (4-10-2026)

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Exit 78 can be taken to the Brookville Historic District. (4-10-2026)

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Food at exit 78 is posted to the right. (4-10-2026)

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Exit 78 can additionally be used to reach the famed borough of Punxsutawney, while the northbound leg of the PA 28 truck route is accessed from exit 81 a few miles further east. (4-10-2026)

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The sign at right points the way to exit 78. (4-10-2026)

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Then, in the middle of a construction zone, there is two-mile notice for exit 81, intersecting mainline PA 28 toward Hazen. (4-10-2026)

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Exit 81 can be used to reach the Jefferson County Fairgrounds. (4-10-2026)

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As it makes its way through Brookville, I-80 crosses the Redbank Creek tributary North Fork. (4-10-2026)

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Before the exit, Richards Street (SR 4001) crosses I-80. (4-10-2026)

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Exit 81 is to the right. (4-10-2026)

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I-80 then crosses PA 28. (4-10-2026)

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